مخدر روانگردان صنعتی میتوسین metocin به جای قارچ مجیک ماشروم
ماده مخدر میتوسین به فرمول 4 هیدروکسی ان متیل ان اتیل تریپتامین 4-HO-MET شناخته می شود یک ماده مخدر روانگردان مشابه با سیلوسین است
میتوسین یک آنالوگ سیلوسین است که می تواند اثرات psilocin سیلوسین را تقلید کند در واقع مخدر میتوسین را می تواند مجیک ماشروم تقلبی نامید
میتوسین اولین بار توسط دکتر الکساندر شولیگن ساخته شد
دوز مصرف ان 150 میلی گرم است و تاکنون مرگ با مصرف ان گزارش نشده است
مصرف میتوسین در سال 2012 در کشور سوئد ممنوع اعلام شده است
خرید و فروش میتوسین فعلا در بازار جهانی مانع قانونی ندارد و قیمت 1000 گرم ان بین 100 تا 150 دلار است
ساخت مخدر میتوسین نسبتا راحت است
opium.site: بخور های گیاهی حاوی ماده مخدر کانابیس صنعتی اسپایس ...
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ماده مخدر میتوسین به فرمول 4 هیدروکسی ان متیل ان اتیل تریپتامین 4-HO-MET شناخته می شود یک ماده مخدر روانگردان مشابه با سیلوسین است
میتوسین یک آنالوگ سیلوسین است که می تواند اثرات psilocin سیلوسین را تقلید کند در واقع مخدر میتوسین را می تواند مجیک ماشروم تقلبی نامید
میتوسین اولین بار توسط دکتر الکساندر شولیگن ساخته شد
دوز مصرف ان 150 میلی گرم است و تاکنون مرگ با مصرف ان گزارش نشده است
مصرف میتوسین در سال 2012 در کشور سوئد ممنوع اعلام شده است
خرید و فروش میتوسین فعلا در بازار جهانی مانع قانونی ندارد و قیمت 1000 گرم ان بین 100 تا 150 دلار است
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| توهمات با میتوسین مشابه با ال اس دی است |
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| کپسول ها و پودر مخدر میتوسین |
4-HO-MET, or 4-hydroxy-N-methyl-N-ethyltryptamine, also known as metocin, is a lesser-known psychedelic drug. It is a structural− and functional analog of psilocin as well the 4-hydroxyl analog of MET. 4-HO-MET was first synthesized by Alexander Shulgin. In his book TiHKAL (Tryptamines I Have Known and Loved), the dosage is listed as 10-20 mg. 4-HO-MET produces psilocin-like distortion of color, sound, and form. Very little data exists about the pharmacological properties, metabolism, and toxicity of 4-HO-MET. There have been no reports of deaths from 4-HO-MET, even though people have reported taking doses up to 150 mg,[1] more than an order of magnitude above the effective dose.[2] It has been classified as a controlled substance in Sweden as of May 1, 2012.[3]
هیدروکسی ان متیل ان اتیل تریپتامین-HO-MET 4 طرز ساخت مخدر میتوسین یا
#21. 4-HO-MET
TRYPTAMINE, N-ETHYL-4-HYDROXY-N-METHYL; 4-INDOLOL,
3-[2-(ETHYLMETHYLAMINO)ETHYL]; N-ETHYL-4-HYDROXY-N-METHYLTRYPTAMINE;
3-[2-(ETHYLMETHYLAMINO)ETHYL]-4-INDOLOL
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| [3D .mol structure] |
SYNTHESIS : A
solution of 0.50 g 4-acetoxyindole (see under 4-HO-DET for its preparation) in 5
mL Et2O was stirred and cooled to 0 °C with protection from atmospheric
moisture. There was then added 0.5 mL oxalyl chloride. The reaction mixture was
stirred for an additional 30 min, and the yellow crystalline solid was removed
by filtration and dissolved in 10 mL of anhydrous THF. This was treated with a
40% solution of methylethyl amine in anhydrous Et2O, dropwise, until the pH was
>10. The solvents were removed under vacuum and the residue dissolved in 200
mL CHCl3. This was washed first with 50 mL 0.1 N HCl and then with 50 mL of
saturated aqueous NaCl. After drying with anhydrous MgSO4 and filtration, the
solvent was removed under vacuum. The residue was recrystallized from Et2O to
give 0.60 g (yield 73%) of 4-acetoxyindol-3-yl-N-ethyl-N-methylglyoxylamide with
a mp 179-180 °C. Anal: C,H,N.
To 10 mL of a stirred solution of LAH (1 M in THF under N2), there was added dropwise a solution of 0.57 4-acetoxyindol-3-yl-N-ethyl-N-methylglyoxylamide in 10 mL anhydrous THF. When the addition was complete, the reaction mixture was brought to a reflux for 15 min. After cooling to 40 °C, sufficient water was added to decompose both the reaction complex and the excess hydride. After filtration through Celite (under an N2 atmosphere), the solvent was removed under vacuum, and the solid residue recrystallized from EtOAc/hexane to provide 0.18 g (41%) N-ethyl-4-hydroxy-N-methylindole (4-HO-MET) with a mp 118-119 °C. Anal: C,H,N.
DOSAGE : 10 - 20 mg, orally
DURATION : 4 - 6 hrs
QUALITATIVE COMMENTS : (with 20 mg, orally) "Qualitatively a lot like psilocin. I started within the first half-hour, and at the max, I felt the same alteration of color and form, and times, sound was felt. As with psilocin, the experience was wave-like, with an alteration of effects between near-normal perception at one minute, only to be swept up in a swirl of altered concept the next minute.
EXTENSIONS AND COMMENTARY : First, an apology for just a single entry in the comments section. This, and several other of these substituted hydroxy and methoxy tryptamines, had had earlier evaluations, but the notes are not at hand and cannot be used. Much will have to come back from memory, and there must be an appropriate fuzziness allowed for the concluded generalization as to dose and duration. With this particular compound, some of the original observations suggested that it was more potent than psilocin, certainly more dramatic. But at the bottom line, I doubt that this ethyl homologue, or the isopropyl homologue 4-HO-DIPT for that matter, could be distinguished from the methyl counterpart psilocin in any blind clinical study.
What's to choose between them? From the view-point of synthesis, the cost and availability of the secondary amine will certainly be a factor. Both methylethyl amine and methylisopropylamine are available, but are quite expensive. Dimethylamine, on the other hand, is dirt cheap but it is a recognized precursor to DMT and thus is difficult to find. In any events, the dimethyl compound is widely available in the mycological arena, and I suspect it would be simplest to stay with nature.
To 10 mL of a stirred solution of LAH (1 M in THF under N2), there was added dropwise a solution of 0.57 4-acetoxyindol-3-yl-N-ethyl-N-methylglyoxylamide in 10 mL anhydrous THF. When the addition was complete, the reaction mixture was brought to a reflux for 15 min. After cooling to 40 °C, sufficient water was added to decompose both the reaction complex and the excess hydride. After filtration through Celite (under an N2 atmosphere), the solvent was removed under vacuum, and the solid residue recrystallized from EtOAc/hexane to provide 0.18 g (41%) N-ethyl-4-hydroxy-N-methylindole (4-HO-MET) with a mp 118-119 °C. Anal: C,H,N.
DOSAGE : 10 - 20 mg, orally
DURATION : 4 - 6 hrs
QUALITATIVE COMMENTS : (with 20 mg, orally) "Qualitatively a lot like psilocin. I started within the first half-hour, and at the max, I felt the same alteration of color and form, and times, sound was felt. As with psilocin, the experience was wave-like, with an alteration of effects between near-normal perception at one minute, only to be swept up in a swirl of altered concept the next minute.
EXTENSIONS AND COMMENTARY : First, an apology for just a single entry in the comments section. This, and several other of these substituted hydroxy and methoxy tryptamines, had had earlier evaluations, but the notes are not at hand and cannot be used. Much will have to come back from memory, and there must be an appropriate fuzziness allowed for the concluded generalization as to dose and duration. With this particular compound, some of the original observations suggested that it was more potent than psilocin, certainly more dramatic. But at the bottom line, I doubt that this ethyl homologue, or the isopropyl homologue 4-HO-DIPT for that matter, could be distinguished from the methyl counterpart psilocin in any blind clinical study.
What's to choose between them? From the view-point of synthesis, the cost and availability of the secondary amine will certainly be a factor. Both methylethyl amine and methylisopropylamine are available, but are quite expensive. Dimethylamine, on the other hand, is dirt cheap but it is a recognized precursor to DMT and thus is difficult to find. In any events, the dimethyl compound is widely available in the mycological arena, and I suspect it would be simplest to stay with nature.
ماده شیمیایی مشابه قارچ جادویی چیست -میتوسین مخدر روانگردان جدید -مخدر میتوسین -روانگردان میتوسین چیست -اثرات مخدر میتوسین چیست -عوارض مخدر میتوسین چیست علائم مصرف میتوسین چیست -روانگردان جدید میتوسین چیست مخدر جدید میتوسین چیست ماده مخدر روانگردان صنعتی جدید میتوسین چیست روانگردان میتوسین چیست مخدر صنعتی میتوسین چیست مخدر توهم زایی میتوسین چیست مخدر روانگردان میتوسین روانگردان مشابه با مجیک ماشروم مخدر مشابه با قارچ جادویی
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