Tazobactam/تازوباکتام

Tazobactam/

تازوباکتام


Tazobactam
Tazobactam structure.svg
Tazobactam ball-and-stick.png
Systematic (IUPAC) name
(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy
category
  • B
Routes of
administration		 Intravenous
Legal status
Legal status
  • ℞ (Prescription only)
Identifiers
CAS Number 89786-04-9 Yes
ATC code J01CG02 (WHO)
PubChem CID 123630
DrugBank DB01606 Yes
ChemSpider 110216 Yes
UNII SE10G96M8W Yes
KEGG D00660 Yes
ChEBI CHEBI:9421 
ChEMBL CHEMBL404 Yes
Chemical data
Formula C10H12N4O5S
Molar mass 300.289 g/mol
 Yes (what is this?)  (verify)
Tazobactam is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as its sodium salt, tazobactam sodium.
Tazobactam is combined with the extended spectrum β-lactam antibiotic piperacillin in the drug piperacillin/tazobactam, used in infections due Pseudomonas aeruginosa. Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express β-lactamase and would normally degrade piperacillin.
Tazobactam is a heavily modified penicillin and a sulfone.
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