Introduction
Quick guide to the most popular nootropic
supplements. All can be stacked, or taken alone.
Neurostim+C™ is
a good premade stack, though I like to add piracetam to it when I need to concentrate in order to
learn (only 4 more months of grad school at night, yay). All of these typically
take days to weeks to make a noticeable improvement on concentration and focus,
and are best taken in longer periods (2-3 months) followed by down time of one
month. As with all supplements, start with the basics, and move on from
there.
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Piracetam
(2-oxo-Pyrrolidine Acetamide) - is a
derivative of the neurotransmitter GABA (Gamma Amino Butyric
Acid). Chemically related to the amino acid Pyroglutamic Acid (Pyrrolidine Carboxylic
acid), which occurs in cerebrospinal fluid and plays an important role in
cognitive functioning.
Biochemical Effects
- Enhances Brain Metabolism (By increasing
Glucose Utilization, Blood & Oxygen Flow){Boosts mental energy &
cerebral circulation}
- Increases Cerebral Phospholipids &
Cellular Membrane Fluidity (By interacting with the polar head moieties of the
phospholipid bilayer) {Supports healthy neuron communication &
structure}.
- Supports Cognitive Receptors (By amplifying
the density of the Muscarinic Cholinergic {Frontal Cortex, Striatum, &
Hippocampus}, NMDA (N-Methyl-D-Aspartate) {Hippocampus}, & AMPA
(Alpha-amino-3-hydroxy-5-Methyl-4-isoxazole-Propionic Acid) Cerebral Cortex
Receptors {Strengthens neurotransmitter receptors involved in memory and
neuroprotection}
- Stimulates the Corpus Callosum, an area of
the brain that controls communication between the left and right hemispheres
(Increases communication between both hemispheres) {Involved in speech and
creative thinking}.
- Stimulates the Locus Coeruleus, (specialized
neurons) {Involved in information processing, attention, cortical/behavioral
arousal, learning and memory}
- Inhibits Platelet Aggregation (By increasing
Red-White blood cells & Platelet deformability, inhibiting thromboxane A2
synthetase or antagonism of thromboxane A2, reducing von Willebrand's factor
& fibrinogen levels) {Supports Healthy Blood
Flow}.
- Decreases EEG complexity (Increases
cooperatively of brain functional processing) {Positively effects
Neuro-Electrical Functioning}.
- Has a significant antioxidant
effect.
- Piracetam positively supports healthy
cognitive & cardiovascular functioning by a multifaceted means of
action.
Notes Approved & used since 1970’s worldwide (Europe, Asia,
and South American) for various health conditions. Recommended by many
healthcare professionals and health organizations, such as the Life Extension
Foundation, as a Nootropic. Piracetum is the first step in the use of nootropics, it
also stacks nicely with all of the following.
Dose 2-6 grams
daily
When can I feel it? Works within an hour to a few
days.
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Aniracetam
Aniracetam (1-Anisoyl-2-pyrrolidinone) is
a fat soluble potent analog of Piracetam.
Biochemical
Effects Similar to
Piracetam, but due to its fat solubility its effects last longer and is far more
potent.
- Helps increase communication between your
left and right sides of the brain, resulting in improved creatively, perception,
and more.
- Has an more potent AMPA receptor enhancing
effect than Piracetam, resulting in better focus and
concentration.
- Been reported to be best ‘cetam for
anti-anxiety effects
Dose 750-1500 mg Daily with meals
When can I feel
it? Works within an hour to a few
days.
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Oxiracetam
(4-hydroxy-2-oxo-1-pyrrolidinacetamide)
is a potent fast acting water soluble analog of Piracetam. Works faster than all
other racetams.
Biochemical Effects
Similar to
Piracetam, but much stronger than Aniracetam and far faster acting. The preferred premium
Nootropic for the elite smart drug user.
- Supports multiple aspects of
Cognition
- Boosts Brain ATP levels (Mental
Energy)
- Increase Choline Acetylcholinetranferase the neuro-enzyme that
creates Acetylcholine (in the cerebral cortex, hippocampus and striatum) {Memory
Support}
Dose 800-1600 mg Daily
When can I feel it? Works within an hour to a few
days.
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Pramiracetam
Pramiracetam
(N-{2-(diisopropylamino)ethyl}-2-oxo-1-pyrrolidine-acetamide) is a fat soluble
potent analog of Piracetam, the most potent Racetam compound being about 15
times stronger than Piracetam.
Dose 100-300mg
daily
Availability Sporadic due to customs
issues.
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L-Huperzine A
Huperzine A is a natural plant alkaloid (extracted from Huperzia serrata), which quickly
and potently boosts memory, learning, and concentration. Used worldwide for
decades in adults and high school students. Is considered the most potent short
term memory enhancer available.
Biochemical
Effects
- Potently raises Acetylcholine (main memory
neurotransmitter) by inhibiting its breakdown from
Acetylcholinesterase.
- Strengthens the Brain's NMDA receptors
(Enhances Focus, Learning, and Brain
Functioning)
Dose Take 200-400 mcg daily for best results with
meals.
When can I feel it? Works within an hour to a few
days.
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Alpha GPC
(Alpha L-GlycerylPhosphorylCholine), also known as
choline alfoscerate, is an unique NeuroActive form of choline that rapidly
penetrates the blood brain barrier, naturally found in small amounts in milk and
soybeans.
Biochemical
Effects
- A precursor for the neurotransmitter
AcetylCholine [Supports Memory]
- A precursor for PhosphatidylCholine
[Supports Brain Structure]
Dose 300-2000 mg
daily.
When can I feel it? Works within a few
days.
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Vinpocetine
(Ethyl Apovincamine) is a derivative of
vincamine (a phytonootropic from periwinkle). While less potent as a mental
stimulant than vincamine, Vinpocetine is the preferred nootropic for Enhancing
blood flow to the Brain, Eyes, and Ears. Its effects on Cerebral Blood Flow far
exceeds all other nootropics.
Biochemical
Effects
- Enhances Brain Metabolism (By increasing
Glucose Utilization, Blood & Oxygen Flow) (Boosts mental energy &
cerebral circulation)
- Stimulates the Locus Coeruleus, (specialized
neurons) (Involved in information processing, attention, cortical/behavioral
arousal, learning and memory)
- Inhibits Platelet Aggregation (Reduces
abnormal blood clots).
- Has a significant antioxidant
effect.
Dose 20-40 mg daily with
meals.
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Theanine
(gamma-ethylamino-L-glutamic acid) is an
unique amino acid found in trace amounts in green tea. It converts in the brain
into GABA, the neurochemical involved in inhibiting over active mental
activities, such as stress, anxiety, worrying, and nervousness. Unlike herbs theanine protects & enhances Cognition, without
causing sleepy or drowsiness.
Biochemical
Effects
- Instant relaxation due to its potent effects
on raising GABA
- Unlike the supplement GABA it passes through
the blood brain barrier readily and has superior GABA raising
effects.
- Has been studied compared to Paxil.
Notes In Japan it is used in soft drinks much like caffeine is added in the US, but to relax rather than
stimulate the mind.
Dose 200-1000mg daily.
When can I feel it?
Works within a
few
hours.
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Acetyl-L-Carnitine
(2-Acetoxy-3-(trimethylaminium)butanoic
acid) is an amino acid-like compound related to Choline found in high levels in
brain cells.
Biochemical Effects
- Increases Acetylation of Coenzyme A (a precursor to Acetylcholine) [Memory
Enhancer]
- Enhances transport of fatty acids into the
mitochondria [Increased Cellular Energy
Levels]
Dose 500-3000mg
daily
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Choline
Choline supplements should be taken
during the administration of all nootropics. Lecithin (caps and granules) is a
cheap choline source. Lecithin should be taken in doses of 5-8 grams daily to
support the nootropics. Alpha GPC (listed above) is another source for choline. It
is more effective / more expensive, but only requires dosing in the 1-3 gram
range to support choline levels in the
brain.
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Vasopressin
Definitely the most euphoric of the memory-enhancing
intelligence-increase drugs outside of the one being called "Euphoria" (more on Euphoria later). Vasopressin is marketed as Diapid, a
prescription drug made by our old friends Sandoz. It can also be ordered as
Vasopressin through chemical supply houses by those who know the ropes. I had
five squirts of Vasopressin out of a nasal inhaler. I was surprised by how
strong the effects were. I had that charged-up hyperconfident rush that one
experiences with cocaine, but combined with much clearer ideation and
without the numbing and discomfort or the strange and disquieting hard edges
which often accompany even the more euphoric coke highs. It
didn't last very long, about two hours, most of which unfortunately spent riding
the BART and walking. By the time I got home, the experience had pretty well
dissipated. I did not have an opportunity to experience Vasopressin as a work/writing
drug. It was clear, however, simply from reading (I was reading "Gravity's
Rainbow" at the time and I consider that a fairly challenging test of
comprehension) on the BART ride home, that Vasopressin is an excellent tool for
rapid learning and comprehension of complex systems of
thought.
The only other time I had Vasopressin, it was in the form of Diapid. I
had only two squirts at a party late at night on top of fairly substantial
amounts of marijuana and alcohol. It didn't noticeably cut through the depressant
effects of those drugs. However, I did experience an intensified and prolonged
orgasm!
Safety & Warnings It is a naturally
occurring peptide that can cause a wide variety of effects beyond those
mentioned in the article. It strains the heart by reducing the heart's food and
oxygen supply and increasing the heart's workload by increasing blood pressure.
In individuals with hidden or overt heart problems, this can mean a heart
attack. In addition vasopressin can cause a dangerous elevation in brain fluid
pressure, leading to stroke, coma, or death.
Also it can produce vertigo, circumoral pallor,
pounding headaches, cramps, diarrhea, gas, nausea, vomiting, urticaria,
difficulty breathing, anaphylactic shock, and normal shock.
It is dangerous to use in people with a history of
epilepsy, migraine, asthma, heart failure, or poor kidney function. Vasopressin
can have dangerous interactions with most stimulants, including pemoline, caffeine, diet pills, and
cold medications.
Overall vasopressin is a real Pandora's
Box, but fortunately there is ongoing research to develop safer and more
effective
alternatives.
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Hydergine
The invention of one Dr. Albert Hoffmann of Sandoz Laboratories. I
know of many people who got their hands on buckets of this stuff and I know of
nobody who continues to take it. The effects are said to be cumulative rather
than immediate and everybody seems to lose interest. "I forgot to take my
Hydergine" is a term which one often hears from chagrined "intelligence agents,"
fully cognizant (even without Hydergine) of the ironies involved. This probably
says more about the people that I hang out with than about Hydergine as an
intelligence increase agent.
Incidentally, Dr. Hoffmann told a friend
of mine that one can get exactly the same effects one gets from daily megadoses
of Hydergine by using 25 micrograms of LSD daily. I have not experimented with subthreshold acid
as an IQ substance, so I cannot comment.
Safety &
Warnings It is an ergot alkaloid, the same chemical class as LSD, but with no psychedelic or immediate effects. It is
currently prescribed to help alleviate some of the symptoms of Alzheimer's
disease, but, despite the tremendous numbers of people with this affliction,
Hydergine is not widely used, mainly because it is only effective in about 1/3
of the people using it. As a matter of fact it worsens cognition in about 1/3 of
people. It
is dangerous to use in individuals with any history of psychosis, low or high blood pressure, heart disease, pregnant
women (at any point in pregnancy), or a history of
migraines. Hydergine has caused rashes, drug fever, headaches, dizziness, vision
problems, appetite loss, nausea, vomiting, cramps, fainting, sluggishness,
drowsiness, emotional withdrawal, apathy, nervousness, hostility, confusion,
depression, weakness, collapse, and
coma.
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Lecithin,
Choline
(with Vitamin C and B6) While perhaps less intriguing and
glamorous to technophilic reality hackers, most of these easily available
cognitive enhancers have a substantially perceptible effect. LECITHIN seems to
be the exception. Even at "Durk and Sandy" dosage levels there was no noticeable
enhancement of focus, recall, etc. CHOLINE and INOSITOL, at about three grams
each, produce mild but definite results with no discomfort and can be used
daily. I did this once for about a month and found myself losing my sense of
humor. However, if you're already humorless you might just as well give this a
go. PHENYLALANINE is quite speedy. While it can be used for creativity and
focus, it tends to make one irritable. For emergency use
only.
Safety & Warnings These compounds are both basically safe
and effective if not spectacular. I would add a few notes though. Use caution
with these if you have a history of epilepsy. Choline may be more effective when
taken with inositol. B6 is more effective and better for you when taken in
wide-spectrum mega-B vitamin supplements. PHENYLALANINE is neurotoxic and can cause
brain damage in about 2% of the population [uploader's note: the 2% with the
metabolic disorder PKU, that is], and it's probably not good in large doses for
anyone. TYROSINE on the other hand is not toxic and is a more effective
substitute. DEANER can be made more effective by combining it with METHIONINE, but be
cautious of large doses of methionine if you have a history of psychosis. In
addition, there are other nutrients that are save and effective in increasing
psychological energy in most people, INOSINE, CYTOCHROME C, LYSINE, and
GINSENG.
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Deaner
This is getting really popular with the
"health food set." Experientially, the effect is very subtle but noticeable.
I've tried this a few times and what I've found is that if I already have a task
to do, I will do it and, in retrospect, I will realize that I sustained my
attention for an unusually long time without flagging or needing a break.
However, if I use this (as I often do with other cognitive enhancers) without a
precise sense of what the task at hand is, it doesn't clarify and help to
motivate activity. This is an important point. Drugs such as Vasopressin, Pemoline,
Euphoria and THA can actually cut through confusion and ennui and help invoke
will. My guess is that most of these substances also work, to varying degrees,
on the pleasure centers of the brain, provoking one's natural 'joie di vivre'
and thereby provoking enthusiasm for creative and organizational
activities.
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Pemoline
Usually combined with Magnesium. The
information most frequently passed around in reference to MAGNESIUM PEMOLINE was
published by the Church of the Tree of Life some years ago in their publication
"Bark Leaf". It recommends taking "Mag-Pem" at 50-100 mgs. every day for two
months in order to substantially increase your I.Q. OUCH! This program is a sure
ticket to severe headaches and extreme nervousness. However, in the 20-30
milligram range, I've found that this can be used twice weekly with excellent
results. The lift is very substantial and
noticeable.
I, and several of my friends, find it particularly good for writing, both
creative and functional. For rapid-fire associations and grand synthesis just
combine it with moderate amounts of Cannabis (Sativa, if possible). It lasts about twelve
hours, coming on slowly and having its greatest effect at around the fifth
through the tenth hours. Clarity and verbal acuity are the strong points here.
At times, the sheer mass of information, new thoughts and connections can
overwhelm and put one into a rather confused state, particularly if one is not
applying oneself to something. When this occurs I find that I can slow down my
thoughts to a point where there is coherence simply by verbalizing them or
writing them down. Unlike its close cousin "EUPHORIA," Pemoline is emotionally
bland. It
is not a pleasure drug. WARNING: from my observations, approximately one in
every ten people get nothin' but headaches from even small doses of
Pemoline.
Safety &
Warnings PEMOLINE is an interesting drug at the center of some
current research. Unfortunately, it is not known how the drug works. If it was,
a safer alternative could be found. Pemoline has caused fatal liver failure,
still births, La Tourette's Syndrome, seizures, hallucinations, uncontrollable
movements of the tongue, lips, face, eyes, and extremities, depression,
delirium, dizziness, irritability, headaches, drowsiness, insomnia, anorexia,
nausea, and cramps. Caution should be used when combining it with any other drug
because it is known to have strong dangerous interactions with many drugs.
Finally, pemoline, a controlled substance, is recognized by the government as
having an abuse/addiction
liability.
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PRL-8-53
Untried by your reviewer at this time.
However, Durk Pearson is quoted in 'High Frontiers' as saying that "PRL-8-53 is
a terrific memory enhancer. Normally you can memorize about seven or eight
digits just by looking at them for a second. PRL-8-53 gives the average person a
memory span of about 21 to 22 digits." He also reported that one amnesia victim
was cured with one dose.
Safety &
Warnings I could find no information on this, even in the most up to
date references. The fact that it still is referred to by its code number
probably means that it is still highly experimental; they may not even know what
its structure is yet. It might be safe, but you are playing neurochemical
roulette.
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THA
Untried by your reviewer at this time. Again, Durk Pearson,
this time in 'High Frontiers/Reality Hackers Newsletter:' "In combination with
arecoline, THA has been found to be remarkably effective as a memory improver
... it's important that the dosage be individualized ... too much will actually
impair memory and produce sweating, excessive muscle tone and mouth-watering."
The standard dosage is "1 to 2 mg." however, Durk recommends that you start with
a quarter of that every two to four hours and work up - if you get those side effects, back
off.
Safety &
Warnings This
is potentially very dangerous. It is an acetylcholinesterase inhibitor making
its actions closely related to Nerve Gas, Pesticides and Strychnine. BE
CAREFUL!
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Centrophenoxine
Centrophenoxine is an intelligence booster
and also an effective anti-aging therapy. It has been shown to cause
improvements in various aspects of memory function and a 30% increase in
lifespan of laboratory animals.
One of the most widely recognized aspects of aging is the buildup of
lipofuscin in brain cells (lipofuscin is the stuff that age spots are made of.)
Centrophenoxine removes lipofuscin deposits from brain cells and reduces its
rate of accumulation in young brain cells. It also rejuvenates the synaptic
structure - the area where the actual transfer of information takes place
between nerve cells.
PRECAUTIONS: Centrophenoxine should not be used by persons who are
easily excitable, people with severe arterial hypertension, or those subject to
convulsions or involuntary musculoskeletal movements. The drug also should not
be used by nursing mothers. Adverse effects are rare, but include
hyperexcitability, insomnia, tremors, motion sickness, paradoxical drowsiness,
and depression. There is no toxicity of Centrophenoxine at therapeutic
doses.
DOSAGE: Take
1000 to 3000mg per day. Centrophenoxine takes effect very quickly. You'll notice
an increase in alertness and a slight stimulating
quality.
SOURCES:
Centrophenoxine is not sold in the United States. It can be purchased over the
counter in Mexico or by mail from the address
below.
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Choline
Choline can be found in several forms including
choline bitartrate, choline chloride, or phosphatidyl choline. Phosphatidyl
choline (PC) is the active ingredient of lecithin. All of these forms of choline
will produce memory boosting effects, but PC has some unique effects as
well.
Choline compounds,
including PC, are able to pass through the blood-brain barrier, where the brain
utilizes the choline to make acetylcholine (a neurotransmitter that plays an
important role in memory). Thus, choline enhances memory by increasing the
amount of acetylcholine available for memory and thought
processes.
PC has some
other important health benefits. It functions as a source of structural material
for every cell in the human body, particularly those of the brain and nerves. It
also aids in the metabolism of fats, regulates blood cholesterol, and nourishes
the fat-like sheathes of nerve fibers.
PRECAUTIONS: Any compound that acts like a
precursor to acetylcholine such as choline, PC, or DMAE should not be used by
people who are manic depressive because it can deepen the depressive phase.
Choline bitartrate and choline chloride can sometimes cause a fishy odor or
diarrhea. PC, however, does not have either of these
effects.
DOSAGE:
Take 3 grams of choline per day in three divided doses. If you're taking
lecithin you need to take a lot more because only part of the lecithin is
choline. Often the label will provide information on the quantity of choline per
tablespoon. All forms of choline should be taken with one gram per day of
vitamin B-5 so that the choline can be converted into
acetylcholine.
SOURCES: Choline and lecithin are considered nutritional
supplements and can be found at health food or drug stores. Commercial lecithin
usually contains other oils and phosphatides besides phosphatidyl choline. Look
at the label before you buy and make sure the product contains more than 30%
phosphatidyl choline. Also, you should taste your lecithin and make sure it does
not taste bitter (this indicates rancidity). Much lecithin on the market is
rancid. The best form of lecithin I know is Twin Labs brand "PC 55" - it
contains 55% PC and is always very
fresh.
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DHEA
Dehydroepiandosterone (pronounced dee-hi-dro-epp-ee-an-dro-ster-own) is a
steroid hormone produced in the adrenal gland. DHEA is the most abundant steroid in the human
bloodstream. Research has found it to have significant anti-obesity, anti-tumor,
anti-aging, and anti-cancer effects. DHEA levels naturally drop as people age
and there is a good reason to think that taking a DHEA supplement may extend
your life and make you more youthful while you're alive. Additionally, DHEA may
be an important player in cognitive enhancement.
DHEA is involved in protecting brain neurons from
senility-associated degenerative conditions like Alzheimer's disease. Not only
does the neuronal degenerative condition occur most frequently at the time of
lowest DHEA levels, but brain tissue contains more DHEA than is found in the
bloodstream. In an experiment with brain cell tissue cultures, Dr. Eugene
Roberts found that very low concentrations of DHEA were found to "increase the
number of neurons, their ability to establish contacts, and their
differentiation." DHEA also enhanced long-term memory in mice undergoing
avoidance training. Perhaps it plays a similar role in human brain
function.
DOSAGE of
DHEA ranges from 50 mg to 2000 mg per day. There is no solid information
indicating an optimal dosage for humans, but, if you want to get serious, you
can get your DHEA levels checked every few months (for about $65), each time
raising the amount of DHEA you take. When your blood levels reach what is normal
for a 20-year-old human, then you're taking enough.
SOURCES: DHEA is now being used by many people
with AIDS because of its immune enhancement and antiviral effects. DHEA is not
FDA approved but AIDS buyers groups are able to sell it to members because the
FDA has a policy of looking the other way when it comes to the activity of these
groups.
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Hydergine (Ergoloid
Mesylates)
Research in other countries has shown that Hydergine improves mental
function, prevents damage to brain cells, and may even be able to reverse
existing damage to brain cells. Hydergine acts in several ways to enhance mental
capabilities and slow down or reverse the aging processes in the brain. Its wide
variety of effects include the following:
1. Increases in blood supply to the
brain. 2. Increases the amount
of oxygen delivered to the brain. 3. Enhances metabolism in brain cells. 4. Protects the brain from damage during periods of
decreased and/or insufficient oxygen supply. 5. Slows the deposit of age pigment (lipofuscin) in
the brain. 6. Prevents free
radical damage to brain cells. 7. Increases intelligence, memory, learning and
recall. 8. Normalizes systolic
blood pressure. 9. lowers
abnormal high cholesterol levels in some cases. 10. Reduces symptoms of tiredness, dizziness, and
tinnitus (ringing in the ears).
One way that Hydergine may enhance memory and learning is by mimicking
the effect of a substance called nerve growth factor (NGF). NGF stimulates
protein synthesis that results in the growth of dendrites in brain cells.
Dendrites facilitate communication throughout the central nervous system and are
necessary for memory and learning. New learning requires new dendritic
growth.
PRECAUTIONS:
If too large a dose is used when first taking Hydergine. it may cause slight
nausea, gastric disturbance, or headache. Overall, Hydergine does not produce
any serious side effects, it is non-toxic even at very large doses, and it is
contraindicated only for individuals who have chronic or acute
psychosis.
DOSAGE:
The US recommended dosage is 3 mg per day; however, the European recommended
dosage is 9 mg per day, taken in three divided doses. Most of the research has
been done at levels of 9 to 12 mg per day. It may take several weeks before you
notice the effects of hydergine.
SOURCES: Hydergine is available in the United States and you can
buy it if you have a doctor's prescription, but keep in mind that your doctor
may not be familiar with the uses I have discussed. It can also be purchased
over the counter in Mexico or by mail from overseas (see
below).
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Sulbutiamine
(Arcalion)
Sulbutiamine is a new compound that has been described as being like
Hydergine only better. It has been shown to facilitate wakefulness, improve
long-term memory, speed up reaction time, decrease anxiety, and increase overall
resistance to stress.
DOSAGE: To combat fatigue take two 200mg tablets per day, always
with breakfast or an AM meal, for a period of 20 days. Do not exceed three
tablets at any time as this very powerful substance may cause severe headaches.
Other than this, Sulbutiamine has no known adverse side
effects.
SOURCES:
Sulbutiamine is not sold in the United States. It can be purchased by mail order
from the address
below.
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Vasopressin
(Diapid)
Vasopressin is a brain hormone that is released by the pituitary gland.
It improves attention, concentration, memory retention, and recall (both
short-term and long-term). Vasopressin facilitates more effective learning by
helping to "imprint" new information in the memory centers of the brain, a
function which cannot be achieved without the action of
vasopressin.
Cocaine, LSD,
amphetamines, Ritalin, and Cylert (pemoline) cause a release of
vasopressin. Frequent use of these drugs can deplete levels of vasopressin with
a result of making you slow and dopey. If you feel burnt out, a whiff of
vasopressin can transform your experience in about 10 seconds because it
is a direct application of the specific brain chemical that has been
depleted.
Alcohol and marijuana, however, inhibit the release of vasopressin. A
whiff of vasopressin when using these drugs will compensate for much of the
dopiness caused by them.
Vasopressin is very useful in situation where there is a large amount of
new information to learn. It increases your ability to memorize and recall
specific factual information.
PRECAUTIONS: Vasopressin usually produces the following side
effects: runny nose, nasal congestion, itch or irritation of the nasal passages,
headache, abdominal cramps, and increased bowel movements. Vasopressin has not
been proven safe for use during pregnancy.
DOSAGE: Vasopressin usually comes in a nasal
spray bottle. Most studies showing memory improvement have been done with a dose
of 12 to 16 USP per day or about two whiffs three or four times per day.
Vasopressin produces a noticeable effect within
seconds.
SOURCES:
Vasopressin is available in the United States. You can buy it if you have a
doctor's prescription, but keep in mind that your doctor may not be familiar
with the uses I have discussed. It can also be purchased over the counter in
Mexico or by mail from overseas (see
below).
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Vinpocetine
(Cavinton)
Vinpocetine, like Piracetam, is a nootropic drug and a powerful memory
enhancer. It facilitates cerebral metabolism by improving cerebral
microcirculation (blood flow), stepping up brain cells' production of ATP (the
cellular energy molecule), increasing the brain's use of glucose, and increasing
the brain's oxygen utilization. Vinpocetine is often used for the treatment of cerebral circulatory
disorders such as memory problems, aphasia, apraxia, motor disorders, dizziness,
and headache.
PRECAUTIONS: Adverse effects are rare, but include hypotension and
tachycardia. It has no drug interactions, no
toxicity, and is generally very safe.
DOSAGE: One or two 5 mg. tablets per
day.
SOURCES:
Vinpocetine is not sold in the United States. It can be purchased by mail from
the address below.
MAIL
ORDER: A little known FDA
ruling now allows the importation of a three-month personal supply of drugs as
long as they are regarded as safe in other countries. Ordering safe but
unapproved drugs is now legal under the new FDA pilot guidelines, Chapter 971.
This compromise was made under pressure from AIDS political action groups
because the were being denied access to potentially life-saving
substances.
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